Read on to learn more about molecular profiling.
Molecular Profiling Discussion Guide
Need help getting the conversation started? This guide can help.
Since molecular testing can provide information that may help direct the way your disease is managed, the Cholangiocarcinoma Foundation recommends testing as soon as possible. For this reason, you should talk to your oncologist about molecular profiling as soon as possible after your diagnosis, ideally before a biopsy is performed.
The National Comprehensive Cancer Network® (NCCN®) recommends that doctors perform molecular profiling when the tumor cannot be removed by surgery or when the cancer is metastatic, meaning it has spread to other parts of the body.
However, even if some time has passed since your diagnosis, it may not be too late to talk to your oncologist about molecular profiling.
Molecular profiling can help you and your healthcare team better understand your
cancer and how best to approach it.
Here are some questions you may want to ask your oncologist:
Looking for more help getting the conversation started? This free Molecular Profiling
Discussion Guide can help.
Talk to Your Oncologist Today About Molecular Profiling!
This discussion guide may help start the conversation.
Did You Know?
The latest technology—called next-generation sequencing (NGS)—has made molecular profiling more comprehensive. It can test one tumor sample for hundreds of gene changes or defects at one time.
Ask your doctor about NGS
Cancer is often caused by one or more genes in your body that have changed. There are different types of abnormal gene changes or defects that can cause CCA. Some of these changes include:
Over time, advances in technology have given healthcare professionals the ability to look very closely into the tumor to identify specific gene changes or defects. This kind of detailed tumor study is called
Genetics and genomics are two terms you might come across as you look for information about CCA. While these words sound similar, they mean different things:
Your healthcare team may be able to use molecular profiling to identify the specific genomic mutations unique to your tumor. This information can help them develop a care plan for your unique CCA.
Among your care team, your oncologist is responsible for ordering molecular testing.
If your oncologist performed a biopsy, but did not order molecular profiling, it may not be too late. An additional biopsy may be needed to provide enough tissue for molecular profiling. Talk to your oncologist and ask if molecular profiling is still possible.
Real patients with CCA and their caregivers share their personal experiences with molecular profiling.